Red Yeast Rice Extract Impact on Liver Health: Metabolomic and Biochemical Data

Mo Zhao's dataset contains metabolomic and biochemical results from a study investigating red yeast rice extract's effects on non-alcoholic fatty liver disease in hamsters. The 1.1 MB Excel file includes data on serum lipids, liver function parameters, inflammatory cytokines, and 135 identified differential metabolites. It was last updated on April 15, 2026, and is shared under a CC-BY-4.0 license.

Use Cases

• Train models to predict therapeutic outcomes based on serum lipid and cytokine profiles.
• Analyze metabolic pathway perturbations using the 135 identified differential metabolites.
• Validate computational models of liver disease using histopathological and biochemical endpoint data.
• Investigate correlations between JNK/AP-1/TNF-α signaling pathway markers and metabolic parameters.

Strengths

• Includes data on 135 differential metabolites identified via untargeted metabolomics.
• Contains measurements for 40 hamsters across four distinct experimental groups.
• Provides multiple data types: biochemical assays, ELISA, qPCR, and immunohistochemistry results.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale ML tasks.
• Data is derived from an animal model (hamsters), which may limit direct translation to human biology.

Provenance

Source

Mo Zhao via figshare

Collection Method

Experimental data from a controlled animal study using untargeted metabolomics (UHPLC-QTOF/MS), biochemical assays, ELISA, qPCR, and immunohistochemistry.

Freshness

Last updated 2026-04-15 05:46:35; freshness should be verified.