U.S. Mortality Trends for Cancer and Substance Use Disorders, 1999–2020

CDC WONDER mortality data from 1999–2020, analyzed by Asma Chaudhary, includes 1,789,591 deaths involving both cancer and psychoactive substance use-related mental disorders. The dataset provides age-adjusted mortality rates and annual percent changes by demographics, region, and substance type. It was last updated in March 2026.

Use Cases

• Analyze temporal mortality trends based on age-adjusted mortality rates and annual percent changes from 1999 to 2020.
• Compare demographic disparities in mortality based on reported rates by sex, race/ethnicity, and urban/rural status.
• Assess geographic disparities in mortality burden based on reported regional and state-level AAMR data.
• Investigate substance-specific mortality trends based on the analysis of alcohol, tobacco, and other psychoactive drug categories.

Strengths

• Covers 22 years of U.S. mortality data (1999–2020).
• Analyzes 1,789,591 deaths with dual diagnoses of cancer and substance use disorders.
• Provides age-adjusted mortality rates and annual percent changes for detailed demographic and geographic subgroups.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is contained in a 21.1 KB DOCX file, suggesting a limited scope, likely summary statistics rather than raw records.

Provenance

Source

Centers for Disease Control and Prevention (CDC) WONDER database.

Collection Method

Mortality data obtained using ICD-10 codes C00–D48 (cancer) and F10–F19 (psychoactive substance–related mental disorders).

Time Range

1999–2020

Freshness

Last updated 2026-03-18 05:34:40; freshness should be verified.

Geography

United States, with regional, state, and urban/rural breakdowns.