Cabbage Bolting DNA Methylation and Gene Expression Data from WGBS

Huiling Guo's dataset contains whole-genome bisulfite sequencing (WGBS) data from cabbage (Brassica oleracea) to study DNA methylation during bolting. It includes 10,159 differentially methylated regions (DMRs) identified between vegetative and reproductive leaves from two cabbage accessions. The dataset was last updated on 2026-04-30.

Use Cases

• Identify differentially methylated genes related to reproductive processes based on GO enrichment analysis results.
• Analyze the correlation between DNA methylation levels and gene expression during bolting based on integrated transcriptomic data.
• Study subgenome-level methylation dynamics, such as the MF2 subgenome advantage, mentioned in the description.
• Investigate the role of specific genes like STM and WUS in meristem development based on their methylation and expression changes.

Strengths

• Includes 10,159 differentially methylated regions (DMRs) identified from whole-genome bisulfite sequencing.
• Data integrates transcriptomic data to correlate methylation changes with gene expression levels.
• Compares two biological conditions (vegetative vs. reproductive leaves) across two cabbage accessions.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (71.5 KB), indicating a limited scope, likely summary statistics rather than raw sequencing reads.

Provenance

Source

figshare, author Huiling Guo

Collection Method

Whole-genome bisulfite sequencing (WGBS) performed on cabbage leaf samples.

Freshness

Last updated 2026-04-30 05:38:46; freshness should be verified.