Table 1_Reinfection and ceftriaxone tolerance in a clinical case of recurrent gonorrhoea:

A 2026 case report from figshare details four clinical isolates of Neisseria gonorrhoeae collected between 2022 and 2025. The report integrates tolerance disc testing, growth curves, MDK99 assays, and a Galleria mellonella infection model with whole-genome sequencing to analyze ceftriaxone tolerance and distinguish reinfection from persistence. The dataset is a 342.5 KB DOCX file authored by Izumo Kanesaka and shared under a CC-BY-4.0 license.

Use Cases

• Study antibiotic tolerance kinetics based on MDK99 and growth curve assays described in the report.
• Compare genomic sequence types to differentiate between reinfection and persistent infection as detailed in the results.
• Validate in vitro tolerance assays against in vivo Galleria mellonella infection model outcomes mentioned in the methods.

Strengths

• Includes data from four distinct clinical isolates collected over a multi-year period (2022-2025).
• Integrates multiple complementary assays: tolerance disc testing, MDK99, growth curves, and an in vivo model.
• Provides whole-genome sequencing results for strain typing.

Limitations

• The dataset is a single 342.5 KB case report document; the underlying raw data files are not provided.
• Row count and column-level documentation for any underlying data are unknown.
• The sample size is limited to isolates from a single patient series.

Provenance

Source

figshare

Collection Method

Clinical case study supported by laboratory assays including tolerance disc testing, growth curves, MDK99, Galleria mellonella infection, and whole-genome sequencing.

Time Range

2022 to 2025

Freshness

Last updated 2026-04-23 05:34:59.