Rat Model Data for Gut-Heart Axis Study of Danggui Sini Granule

Haipeng Tang published a dataset on figshare in May 2026. The data likely contains results from a rat model study investigating the cardioprotective effects of Danggui Sini Granule on vasospastic coronary heart disease. The dataset includes pharmacodynamic, gut microbial, and metabolomic measurements.

Use Cases

• Analyze gut microbiota modulation based on 16S rRNA sequencing results mentioned in the description
• Investigate lipid metabolic reprogramming based on untargeted metabolomics data for linoleic and arachidonic acid pathways
• Validate predicted molecular targets based on network pharmacology and molecular docking analyses described
• Study correlations between inflammatory markers and myocardial injury based on TNF-α, IL-6, and histopathology data

Strengths

• Dataset is licensed under CC-BY-4.0, allowing open reuse and modification
• The description details specific analytical methods including 16S rRNA sequencing and untargeted metabolomics
• Results include concrete findings such as modulation of genera like Escherichia and Lactobacillus

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset is very small (34.2 KB), suggesting limited scope or summary-level data

Provenance

Source

figshare

Collection Method

Data likely generated from a laboratory study using a rat model of vasospastic coronary heart disease.

Freshness

Last updated 2026-05-22 04:28:09