Risk Factors for Adverse Outcomes After Modified TROPIS Surgery for High Anal Fistula

A retrospective cohort study by Benfan Yin analyzed 218 consecutive patients who underwent modified TROPIS surgery combined with Parks’ fistulotomy with seton for high anal fistula between May 2022 and May 2024. The dataset likely contains patient-level data used to identify risk factors for a composite postoperative adverse outcome, which occurred in 22.5% of cases. The study identified five independent risk factors, including diabetes mellitus and horseshoe extension, using Firth’s penalized logistic regression.

Use Cases

• Training a binary classification model to predict postoperative adverse outcomes based on identified risk factors like diabetes and BMI.
• Validating the identified risk factors (e.g., internal sphincter incision >50%) in an external patient cohort.
• Conducting a meta-analysis on surgical techniques for high anal fistula using the reported 22.5% adverse outcome rate.

Strengths

• The study includes 218 patient records, providing a defined cohort size.
• Risk factors are quantified with adjusted odds ratios and confidence intervals (e.g., diabetes OR 3.42).
• Model performance is reported with a C-statistic of 0.82 and internal validation via bootstrap.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The data reflects a single-center, two-year study period, which may limit generalizability.

Provenance

Source

Benfan Yin

Collection Method

Retrospective cohort study of consecutive patients.

Time Range

May 2022 to May 2024

Freshness

Last updated 2026-06-01 05:18:28; freshness should be verified.