Vachellia Nilotica Extract Bioactivity and Phytochemical Data

A 13.5 KB dataset by Essam Y. Abdul-Hafeez, published in April 2026, containing experimental results on the bioactivity of a methanolic fruit extract. It documents phytochemical composition, antioxidant capacity (IC50 31.77 μg mL⁻¹), antimicrobial inhibition zones, and selective cytotoxicity against human cancer cell lines. The data originates from in vitro laboratory assays.

Use Cases

• Correlate total phenolic content (419.45 mg GAE g⁻¹) and flavonoid content (245.48 mg QE g⁻¹) with DPPH antioxidant IC50 values.
• Model antimicrobial efficacy using inhibition zone diameters (e.g., 23.00 mm for Acinetobacter johnsonii) against different bacterial and fungal strains.
• Analyze selective cytotoxicity by comparing cell viability percentages (below 5% for cancer cells vs. higher for normal Vero cells) across extract concentrations (500–1000 μg mL⁻¹).
• Validate traditional medicinal uses by linking qualitative phytochemical screening results (tannins, alkaloids, glycosides) to quantified bioactivity metrics.

Strengths

• Contains specific, quantified bioactivity metrics like antioxidant IC50 (31.77 μg mL⁻¹) and total phenolic content (419.45 mg GAE g⁻¹).
• Reports results from multiple standardized assays (MTT, agar well diffusion, colorimetric methods) on three human cancer cell lines and normal cells.
• Data is openly licensed under CC-BY-4.0 for reuse.

Limitations

• Extremely small data volume (13.5 KB), indicating a summary of results rather than a raw experimental dataset.
• No raw columnar data or sample rows are provided; information is embedded in a document format.
• Scope is limited to a single plant extract, preventing comparative analysis across species or compounds.

Provenance

Source

Essam Y. Abdul-Hafeez via figshare.

Collection Method

In vitro laboratory assays including phytochemical screening, DPPH assay, agar well diffusion, and MTT cytotoxicity assays.

Time Range

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Freshness

Last updated April 2026.

Geography

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