Sequential Immune-Related Nephritis and Pneumonitis During ICI Therapy: A Case Report

A single clinical case report details sequential immune-related adverse events during immune checkpoint inhibitor therapy. The report describes a patient who developed severe acute kidney injury followed by pneumonitis during steroid tapering. Authored by Haocheng Zhao and published on figshare under CC-BY-4.0 in May 2026, the dataset is a 115.9 KB PDF document.

Use Cases

• Analyze the temporal sequence of multi-organ immune-related adverse events based on the detailed clinical timeline.
• Study the relationship between steroid tapering and the emergence of new toxicities based on the described patient course.
• Review clinical management strategies for complex irAEs based on the described interventions of high-dose corticosteroids and dose adjustments.

Strengths

• The case provides a detailed, documented sequence of two distinct immune-related adverse events.
• The report includes specific clinical markers, such as a considerable increase in serum creatinine level.
• The dataset is openly licensed under CC-BY-4.0 for reuse.

Limitations

• The dataset is a single case report (n=1), limiting statistical generalizability.
• Row count and column-level documentation are absent; data is embedded in narrative text.
• The 115.9 KB size indicates a very limited scope, containing only one detailed case.

Provenance

Source

Haocheng Zhao

Collection Method

Clinical case documentation.

Freshness

Last updated 2026-05-13 04:29:45.