Pediatric Acute Rheumatic Fever Biomarker Levels and Cardiac Involvement

Serum biomarker measurements for 38 pediatric patients with acute rheumatic fever and 38 matched healthy controls. The dataset includes levels of soluble suppression of tumorigenicity-2 (sST2) and mid-regional pro-adrenomedullin (MR-ProADM) and their association with cardiac involvement assessed by echocardiography. The data was uploaded by Ecem Ipek Altınok on figshare in May 2026.

Use Cases

• Training models to predict moderate-to-severe cardiac involvement based on sST2 and MR-ProADM biomarker levels.
• Evaluating the discriminative performance of biomarkers for acute rheumatic fever diagnosis using ROC analysis.
• Conducting multivariate logistic regression to identify factors independently associated with clinical outcomes in pediatric cardiology.

Strengths

• Includes data from a case-control study with 38 patients and 38 matched controls.
• Biomarker levels are linked to echocardiography-assessed cardiac involvement categorized as mild or moderate-to-severe.
• Statistical results, including AUC values and odds ratios, are provided in the description, indicating analytical depth.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 11.1 KB, indicating limited scope.

Provenance

Source

figshare, uploaded by Ecem Ipek Altınok.

Collection Method

Data likely originates from a case–control clinical study measuring serum biomarkers via enzyme-linked immunosorbent assay.

Freshness

Last updated 2026-05-29 06:13:21; freshness should be verified.