MELD 3.0: Liver Transplant Waitlist Survival by Sex and Age, 2017-2024

95,211 adult liver transplant candidates from the U.S. Scientific Registry of Transplant Recipients were analyzed to evaluate survival disparities. Waitlisted females experienced a 16.28% mean increase in relative 180-day mortality hazard compared to males after MELD 3.0's implementation. This retrospective study by Marissa Di Napoli uses data from January 1, 2017, to September 3, 2024.

Use Cases

• Analyzing sex-based survival disparities based on waitlist mortality data
• Evaluating the impact of the MELD 3.0 scoring system update on patient outcomes
• Modeling time-dependent survival probabilities based on patient age and MELD score
• Conducting risk-adjusted analyses of mortality hazard ratios for different demographic groups

Strengths

• Analysis includes 95,211 patient records from a national registry
• Covers a 7.5-year time range spanning the implementation of MELD 3.0 in July 2023
• Provides specific hazard ratio increases (16.28% for sex, 350% for age) and survival probabilities (65%)

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count for the underlying data table is unknown, which may limit suitability assessment
• Data may reflect geographic and temporal bias inherent to the U.S.-only source

Provenance

Source

Scientific Registry of Transplant Recipients (SRTR) database

Collection Method

Retrospective, cross-sectional patient risk analysis

Time Range

January 1, 2017, to September 3, 2024

Freshness

Last updated 2026-05-25 06:03:25; freshness should be verified

Geography

United States