Table_1_Short-Term Effects of Sacubitril/valsartan on Echocardiographic Parameters in Dogs

21 dogs with symptomatic myxomatous mitral valve disease (MMVD) stage C were studied in a prospective, randomized, single-blind trial. The dataset, authored by Nakkawee Saengklub and last updated in April 2026, compares the effects of sacubitril/valsartan versus ramipril over a 4-week period, measuring echocardiographic, electrocardiographic, and biomarker parameters.

Use Cases

• Compare treatment efficacy for canine heart failure based on echocardiographic indices like LA/Ao and LVIDDN.
• Analyze short-term drug effects on cardiac remodeling based on end-diastolic and end-systolic volume indices.
• Study biomarker correlations with clinical outcomes based on NT-proBNP and urinary aldosterone measurements.
• Benchmark clinical trial design for veterinary medicine based on the prospective, randomized study structure.

Strengths

• Data originates from a controlled, prospective, randomized clinical trial with 21 canine subjects.
• Includes multiple measurement types: echocardiography, electrocardiography, blood pressure, and biomarkers.
• Clear temporal structure with baseline (D0) and 4-week follow-up measurements.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 18.6 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Data collected from a prospective, randomized, single-blind clinical study.

Time Range

Study period includes baseline and a 4-week follow-up.

Freshness

Last updated 2026-04-13 13:46:00; freshness should be verified.

Geography

Spatial coverage is unknown.