Somatosensory Cortex Neuronal Integrity After Subcortical Stroke

Rafay Cheema's dataset contains magnetic resonance spectroscopy data from a study of 14 stroke patients and 10 healthy controls, published on figshare in 2026. It includes metabolic markers of neuronal integrity (N-acetylaspartate) and neurotransmission (glutamate-glutamine) measured in the primary somatosensory cortex. The data was analyzed to investigate correlations with hand impairment in subacute and chronic stroke phases.

Use Cases

• Modeling the relationship between neuronal metabolic markers and motor impairment scores based on Fugl-Meyer assessments.
• Comparing metabolic alterations in subacute versus chronic stroke patient subgroups as described in the analysis.
• Investigating correlations between N-acetylaspartate and glutamate-glutamine levels in post-stroke brains versus healthy controls.

Strengths

• Includes data from a controlled study with 14 patients and 10 matched healthy controls.
• Contains specific metabolic markers (N-acetylaspartate, glutamate-glutamine) measured with 3T MR Spectroscopy.
• Analysis includes multivariate models with covariates like age, sex, and time since stroke.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 20.0 KB, indicating limited scope.

Provenance

Source

figshare, author Rafay Cheema.

Collection Method

Data collected via 3T MR Spectroscopy (Allegra Siemens Medical Solutions) from stroke patients and controls.

Time Range

Study includes patients in subacute (≤6 months) and chronic (>6 months) phases post-stroke.

Freshness

Last updated 2026-05-20 05:46:08; freshness should be verified.