Table 1_Spectrum of autoantibodies and other serological parameters in connective tissue d

Table 1_Spectrum of autoantibodies and other serological parameters in connective tissue disease–associated interstitial lung disease patients.docx contains a cross-sectional analysis of 200 patients from a tertiary care centre in Western India. The dataset compares 90 CTD-ILD patients with 110 non-CTD-ILD patients on demographic, radiological, autoantibody, and serum profiles, including hospitalization and mortality outcomes. The data was authored by Pooja Jaiswal and last updated on 2026-06-03.

Use Cases

• Compare demographic and clinical profiles between CTD-ILD and non-CTD-ILD patients based on age, sex, and radiological patterns mentioned in the description.
• Analyze associations between specific autoantibodies (e.g., anti-SSA/Ro, anti-MDA5) and disease subtypes (e.g., RA-ILD, SSc-ILD) as described.
• Investigate predictors of CTD-ILD based on multivariable analysis results for age, sex, NSIP, UIP, TNF-α, IL-22, and IL-4.
• Study hospitalization patterns and mortality outcomes among CTD-ILD patients based on the reported admission rates and in-hospital mortality.

Strengths

• Dataset includes a specific cohort of 200 patients (90 CTD-ILD, 110 non-CTD-ILD) from a defined geographic region (Western India).
• Analysis includes a wide range of serological parameters, including autoantibodies (ANA subspecificities, anti-MDA5), cytokines (TNF-α, IFN-γ, IL-4, IL-22), and enzymes (LDH, MMP7).
• Results provide statistically significant comparisons (p-values) and adjusted odds ratios (aOR) for key predictors.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic bias inherent to a single-centre study in Western India.

Provenance

Source

figshare, author Pooja Jaiswal.

Collection Method

Single-centre, cross-sectional study using indirect immunofluorescence, line blot assay, ELISA, and multiplex bead-based assays.

Freshness

Last updated 2026-06-03 04:26:55; freshness should be verified.

Geography

Western India.