Oocyte Quality Biomarker Data from a Prospective Cohort Study

From August 2024 to August 2025, a prospective cohort study collected data on 581 mature oocytes from women aged ≤ 38 undergoing IVF cycles at Lee Women’s Hospital. Chun-I Lee authored this dataset, which uses polarized light microscopy to measure spindle and zona pellucida birefringence as noninvasive biomarkers for predicting usable blastocyst formation.

Use Cases

• Predict usable blastocyst formation based on spindle-to-oocyte light retardance ratio (SOLRR)
• Analyze correlations between embryo developmental speed and SOLRR values
• Compare trophectoderm morphology outcomes between high and low SOLRR groups
• Evaluate the predictive power of polarized light imaging parameters alongside anti-Müllerian hormone levels

Strengths

• 581 mature oocytes provide a substantial sample size for analysis
• Includes specific predictive metrics like SOLRR (0.011 ± 0.003) and associated AUC (0.63)
• Prospective cohort design with clear time range (August 2024 to August 2025)

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data is limited to a single hospital and women aged ≤ 38, which may introduce bias

Provenance

Source

Lee Women’s Hospital

Collection Method

Prospective cohort study using polarized light microscopy and time-lapse embryo culture

Time Range

August 2024 to August 2025

Freshness

Last updated 2026-05-05 04:13:03; freshness should be verified