Lymph Node Yield Thresholds for Oral Cancer Survival After Neoadjuvant Therapy

A 2019-2022 study of 455 patients from two Chinese hospitals defines evidence-based surgical benchmarks for neck dissection adequacy in oral squamous cell carcinoma. The research establishes thresholds of 20 total nodes for unilateral dissection and an average of 18 nodes per side for bilateral dissection, linking them to 3-year overall survival outcomes. The dataset, authored by Shuai Yuan and shared under CC-BY-4.0, likely contains patient-level clinical and surgical data used to derive and validate these thresholds.

Use Cases

• Validate surgical quality benchmarks based on lymph node yield thresholds.
• Train survival prediction models based on lymph node count and surgical extent.
• Analyze the association between lymph node yield and major complication rates.
• Compare surgical outcomes between unilateral and bilateral neck dissection procedures.

Strengths

• Derived from a multi-center study with 455 total patients across training and validation cohorts.
• Validated thresholds show good discrimination (C-index for OS: 0.71) and excellent calibration.
• Clear, evidence-based benchmarks (≥20 nodes unilateral, ≥18 average bilateral) linked to survival outcomes.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic bias inherent to the two Chinese hospital sources.

Provenance

Source

Henan Cancer Hospital and First Affiliated Hospital of Zhengzhou University

Collection Method

Clinical study of consecutive patients treated with neoadjuvant immunochemotherapy and surgery.

Time Range

2019-2022

Freshness

Last updated 2026-06-03 05:43:01; freshness should be verified.

Geography

China