ADB-BUTINACA and Metabolites in Post-Mortem Samples from Three Fatalities

Three fatal intoxication cases involving the synthetic cannabinoid ADB-BUTINACA are documented, with post-mortem concentrations measured across 11 biological matrices. The dataset includes femoral blood concentrations ranging from 4.2–8.2 ng/mL and heart blood from 5.7–11 ng/mL, along with tissue and fluid measurements. It was created by Annette Zschiesche and last updated on 2026-05-13.

Use Cases

• Model post-mortem redistribution based on heart-to-femoral blood ratios ranging from 1.3–1.8.
• Identify metabolic biomarkers for synthetic cannabinoids based on metabolite profiles in urine and bile.
• Assess drug stability in stored samples based on the 12-week stability study in whole blood.
• Interpret toxicological significance in fatalities based on the assigned Toxicological Significance Score (TSS) of 1–3.

Strengths

• Concentrations quantified across 11 distinct biological matrices per case.
• Includes a 12-week stability assessment for ADB-BUTINACA in whole blood.
• Provides Toxicological Significance Scores (TSS) for interpreting case findings.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is limited to three cases, representing a small sample size.

Provenance

Source

figshare

Collection Method

Post-mortem samples analyzed via immunoassay, GC-MS, and LC-MS/MS.

Freshness

Last updated 2026-05-13 22:01:23; freshness should be verified.