Systematic Review of Vaginal Irrigation Self-Management for Cervical Cancer Radiotherapy

A systematic review synthesizing evidence from 23 randomized controlled trials on vaginal irrigation self-management for cervical cancer patients undergoing radiotherapy. The review, authored by Zhe Xu and published on figshare in 2026, produced 12 key recommendations across four domains. The evidence was graded using the JBI (2014) system, resulting in conditional recommendations due to the high risk of bias in the included studies.

Use Cases

• Informing clinical practice guidelines based on synthesized evidence from 23 RCTs.
• Designing nurse-led management protocols based on the four recommendation domains: individualized strategies, health education, supervision methods, and support.
• Identifying research gaps for higher-quality confirmatory studies based on the noted limitations of existing evidence.

Strengths

• Systematic methodology covering multiple major databases, including Chinese sources (CNKI, Wanfang Data, SinoMed).
• Synthesizes evidence from 23 randomized controlled trials into 12 actionable recommendations.
• Uses a formal evidence grading system (JBI 2014) to assess and present recommendations.

Limitations

• The underlying data is a 30.7 KB document; the dataset is a review summary, not the primary clinical trial data.
• The review notes a high risk of bias in the included RCTs, which limits the strength of its conclusions.
• Column-level documentation for any extracted data is absent; the file is a narrative document.

Provenance

Source

Zhe Xu via figshare.

Collection Method

Systematic literature review of randomized controlled trials from PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang Data, and SinoMed.

Time Range

Literature search covered records from database inception until August 12, 2025.

Freshness

Last updated 2026-06-03 06:04:54.