Targeting Histamine H4 Receptor in a Murine Breast Cancer Model

A research document details the role of the histamine H4 receptor in breast cancer progression using a murine model. Ramiro Vázquez authored this study, which was last updated on 2026-04-21. The 16.0 KB DOCX file contains findings on tumor cell proliferation, immune response, and energy metabolism.

Use Cases

• Study the anti-tumor effects of H4R blockade based on the described murine model experiments.
• Analyze immune cell recruitment in the tumor microenvironment based on the mention of CD8+ cells.
• Investigate metabolic alterations in cancer cells based on described changes in lactate release and ROS production.

Strengths

• Specific focus on the H4 receptor's dual role in tumor and immune modulation.
• Research includes in vivo and in vitro experimental results from a defined murine model (4T1 cell line).
• Document is under a permissive CC-BY-4.0 license for reuse.

Limitations

• The dataset is a 16.0 KB DOCX text document, not a structured data file.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

figshare

Collection Method

Likely contains experimental data and analysis from a published or preprint study.

Freshness

Last updated 2026-04-21 05:20:24; freshness should be verified.