Review on A-to-I RNA Editing in Normal Hematopoiesis and Leukemia

A scholarly review synthesizing current knowledge on adenosine-to-inosine RNA editing and ADAR enzymes in blood cell development and leukemia pathogenesis. The document, authored by Xiaowei Li, was last updated on May 25, 2026, and is licensed for open use under CC-BY-4.0. It is a 76.8 KB DOCX file hosted on figshare.

Use Cases

• Literature review synthesis based on the compiled knowledge of ADAR functions in hematopoiesis.
• Hypothesis generation for translational research based on the proposed context-dependence of the ADAR1-dsRNA response axis.
• Identifying methodological gaps in leukemia research based on the discussed theoretical and technical limitations.

Strengths

• The document provides a focused review on a specific molecular pathway in hematopoiesis and leukemia.
• It is openly licensed under CC-BY-4.0, permitting broad reuse.
• The author is explicitly named, providing clear attribution.

Limitations

• The dataset is a 76.8 KB document, indicating a limited scope focused on review content rather than primary data.
• Row count and column-level documentation are absent; the content's structure must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Xiaowei Li

Collection Method

Likely a literature review and synthesis.

Freshness

Last updated 2026-05-25 06:03:12; freshness should be verified.