Meta-Analysis of Dietary Nitrate Effects on Weight Management and Blood Lipids

Eight randomized controlled trials involving 199 participants form the basis of this systematic review and meta-analysis. The study, authored by Wenjun Cai and last updated in April 2026, found dietary nitrate supplementation significantly reduced systolic blood pressure and lipid markers like total cholesterol and triglycerides, but had no significant effect on body weight or BMI.

Use Cases

• Evaluating the efficacy of dietary nitrate on systolic blood pressure based on the reported meta-analysis results
• Assessing the impact of nitrate supplementation on lipid parameters like total cholesterol and triglycerides as described in the review
• Investigating the relationship between intervention duration and blood pressure outcomes using the subgroup analysis mentioned
• Analyzing publication bias in obesity-related clinical trials based on the detection noted for BMI and diastolic blood pressure

Strengths

• Adheres to PRISMA 2020 reporting guidelines for systematic reviews, as stated in the description
• Includes results from 8 randomized controlled trials, providing a synthesized evidence base
• Reports specific statistical measures including standardized mean differences, confidence intervals, and I² statistics for heterogeneity

Limitations

• The underlying data file is a 107.6 KB DOCX document, which is a very small text summary and not a raw dataset
• Row count and column-level documentation are unknown, limiting suitability assessment for direct analysis
• The sample size of the included evidence is noted as relatively small (199 participants), which may affect generalizability

Provenance

Source

figshare, author Wenjun Cai

Collection Method

Systematic review and meta-analysis of randomized controlled trials sourced from PubMed, Scopus, Web of Science, and Embase

Time Range

Literature search conducted up to April 2026

Freshness

Last updated 2026-04-28 05:24:29