Table 1_The effect of elevated physiological temperatures on bacterial survival and antibi

A 675.5 KB dataset from figshare, last updated on 2026-05-29, contains results from an in vitro infection prevention model. Robert Kamphof authored this study investigating the effect of temperatures from 32°C to 42°C on bacterial killing, adhesion, and antibiotic susceptibility for three clinical isolates. The data likely includes bacterial load measurements in colony forming units per milliliter (CFU/mL) and dose-response curves for antibiotics cefazolin and gentamicin.

Use Cases

• Modeling the relationship between temperature and antibiotic efficacy based on dose-response curves mentioned in the description.
• Analyzing bacterial load reduction in planktonic and adhered fractions across different temperatures.
• Comparing antibiotic susceptibility changes for Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia coli under physiological temperature ranges.

Strengths

• Data is derived from a controlled in vitro model testing three specific bacterial isolates.
• Experiments were conducted across four distinct temperature points (32°C, 37°C, 40°C, 42°C) with and without two antibiotics.
• Results include specific quantitative findings, such as a 6-log reduction in CFU/mL for Staphylococcus epidermidis at 42°C with 0.1 μg/mL cefazolin.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (675.5 KB), indicating a limited experimental scope.

Provenance

Source

figshare

Collection Method

In vitro laboratory experiments exposing bacterial isolates to varying temperatures and antibiotic concentrations.

Freshness

Last updated 2026-05-29 06:07:21; freshness should be verified.