Meta-Analysis of Sodium-Restricted Diet Effects on Heart Failure Patient Prognosis

A systematic review and meta-analysis of 16 randomized controlled trials involving 2,260 heart failure patients, published up to July 2025. The study, authored by Ming-hao Ma and shared on figshare, evaluates the impact of sodium-restricted diets on mortality, readmission rates, and quality of life. Results indicate such diets may increase mortality risk, particularly for certain patient subgroups.

Use Cases

• Evaluating the association between sodium restriction and all-cause mortality based on the reported risk ratio of 1.50.
• Assessing the effect of sodium restriction on cardiac mortality based on the reported risk ratio of 2.51.
• Analyzing subgroup outcomes for HFrEF patients and those with concurrent fluid restriction and diuretic use.
• Investigating the relationship between dietary sodium and patient quality of life or serum NT-proBNP levels.

Strengths

• Includes data from 16 randomized controlled trials, a standard for clinical evidence.
• Analyzes outcomes for 2,260 heart failure patients.
• Conducts subgroup analyses for HFrEF patients and those with specific co-interventions.

Limitations

• The dataset is a single 18.8 KB document file; the underlying tabular data from the meta-analysis is not provided.
• Column-level documentation is absent; field semantics must be inferred from the article text.
• Row count for the underlying trial data is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of RCTs retrieved from PubMed, Web of Science, Cochrane Library, and Embase.

Time Range

From database inception to July 2025.

Freshness

Last updated 2026-05-01 05:28:28; freshness should be verified.