Carbapenem-Resistant Enterobacteriaceae in Pediatric Patients from Eastern China

281 non-duplicated CRE clinical strains were isolated from children in Suzhou, eastern China. The dataset, created by Yihan Zheng and last updated in May 2026, details antimicrobial susceptibility, resistance gene prevalence, and hypervirulence markers. Klebsiella pneumoniae, Escherichia coli, and Klebsiella aerogenes were the most common strains identified.

Use Cases

• Analyze antimicrobial resistance profiles based on susceptibility testing results mentioned in the description
• Study the prevalence of carbapenemase genes (e.g., blaOXA-232, blaKPC-2) and ESBL genes (e.g., blaTEM-1, blaCTX-M-14) among CRE strains
• Investigate the association between hypervirulence genes (e.g., iucA, rmpA) and patient prognosis in carbapenem-resistant Klebsiella pneumoniae infections

Strengths

• Contains data on 281 non-duplicated clinical isolates, providing a specific sample size.
• Reports detailed prevalence percentages for specific resistance and hypervirulence genes, such as blaOXA-232 (38.08%) and iucA (24.84%).
• Identifies 22 strains (14.01%) as carbapenem-resistant and hypervirulent Klebsiella pneumoniae (CR-HVKP), linking genotype to clinical outcome.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is limited to a single geographic region (Suzhou, eastern China) and pediatric patient population.

Provenance

Source

figshare

Collection Method

Clinical strains were isolated, identified via mass spectrometry, and analyzed for antimicrobial susceptibility and genetic markers using VITEK 2 Compact, Kirby-Bauer method, and PCR sequencing.

Freshness

Last updated 2026-05-28 05:58:21; freshness should be verified.

Geography

Suzhou, eastern China