COVID-19 Impact on Live Birth Rates in Fresh Embryo Transfer Cycles, 2021-2023

A retrospective study of 1,025 fresh embryo transfer cycles from January 2021 to January 2023, comparing pregnancy and neonatal outcomes between patients with and without COVID-19 infection. The dataset, authored by Dan Sun and shared on figshare, includes analysis of live birth rates, miscarriage rates, and outcomes stratified by infection timing, fever, and partner infection status. The study found a lower live birth rate associated with COVID-19 infection, particularly when infection occurred 28–84 days before oocyte retrieval with high fever or when both partners were infected.

Use Cases

• Train models to predict live birth risk based on infection status and timing for patients undergoing fertility treatment.
• Analyze the association between fever severity during infection and adverse pregnancy outcomes in fresh embryo transfer cycles.
• Study the impact of dual-partner infection status on fertility treatment success rates.
• Validate clinical guidelines for proceeding with or canceling embryo transfer procedures in patients with recent infections.

Strengths

• Includes 1,025 clinical cases with a defined comparison between infected (n=263) and non-infected (n=762) groups.
• Analysis provides specific odds ratios for key outcomes, such as an adjusted OR of 0.655 for lower live birth rate in the infected group.
• Stratified analysis examines subgroups based on infection timing, fever ≥ 38.5°C, and partner infection status.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small at 18.6 KB, indicating limited scope and sample size.

Provenance

Source

figshare, author Dan Sun.

Collection Method

Retrospective study analyzing clinical records.

Time Range

January 2021 to January 2023.

Freshness

Last updated 2026-04-17 04:11:48; freshness should be verified.