Vicenin-2 Effects on Skin Photoaging via Macrophage Polarization

A 16.8 KB dataset from figshare, last updated on 2026-03-17, containing results from a study by Yan Zhou on the natural flavonoid Vicenin-2. The data likely includes findings from in vitro experiments on RAW264.7 macrophages and in vivo tests on a mouse photoaging model. It explores the correlation between macrophage subtypes and photoaging, and the mechanism involving m6A modification and the NF-κB pathway.

Use Cases

• Train models to predict macrophage polarization states based on m6A modification levels mentioned in the description.
• Analyze the relationship between KIAA1429 expression and anti-inflammatory M2 macrophage levels as described.
• Study the inhibitory effect of Vicenin-2 on NF-κB pathway activation via p65 phosphorylation data.
• Correlate skin hydration and collagen organization improvements with shifts in M1/M2 macrophage ratios from the experimental results.

Strengths

• Data is associated with a specific, peer-reviewed research hypothesis on Vicenin-2's mechanism.
• The dataset is openly licensed under CC-BY-4.0.
• Platform tags provide clear domain keywords for discovery.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 16.8 KB, indicating limited scope.

Provenance

Source

figshare, authored by Yan Zhou.

Collection Method

Data likely generated from single-cell sequencing analysis and in vivo/in vitro experiments described in the study.

Freshness

Last updated 2026-03-17 13:07:55; freshness should be verified.