NFIA::CBFA2T3 Fusion in Pediatric Erythroid Sarcoma: A Case Report

A figshare document by Marta Brunetti, last updated May 4, 2026, details a rare case of erythroid sarcoma in a 2-year-old boy. The 31.1 KB file reports the identification of an NFIA::CBFA2T3 chimeric fusion, which may define a molecular subgroup of acute erythroid leukemia and erythroid sarcoma. The patient achieved sustained remission following acute myeloid leukemia-like therapy and a stem cell transplant.

Use Cases

• Identifying a potential molecular marker for a rare leukemia subtype based on the reported NFIA::CBFA2T3 fusion.
• Studying the clinical presentation and treatment response of pediatric erythroid sarcoma based on the detailed case description.
• Comparing genetic findings in extramedullary erythroid tumors to systemic acute erythroid leukemia as discussed in the document.

Strengths

• Document is licensed under CC-BY-4.0, permitting open sharing and adaptation.
• Provides a specific, rare clinical case with a 28-month follow-up on patient outcome.
• Focuses on a novel NFIA::CBFA2T3 fusion, a finding of potential diagnostic significance.

Limitations

• The dataset is a 31.1 KB DOCX file, indicating a very limited scope, likely a single case report.
• Row count and column-level data are unknown; the primary content is narrative text.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, author Marta Brunetti.

Collection Method

Likely contains a clinical case report and genetic analysis from a single patient.

Freshness

Last updated 2026-05-04 10:39:11; freshness should be verified.