73 diverse global sheep breeds were analyzed to characterize the allele frequency distribution of the MSTN g.119292288G>A mutation. Yuan Xu published this dataset on figshare in April 2026, which likely contains results from association analyses in a Hu × East Friesian hybrid population. The derived allele was not detected in 31 ancient European sheep genomes dated between 8,200 and 440 years before present.
Use Cases
- Assessing the phenotypic impact of the MSTN mutation based on birth weight, weaning weight, and six-month body weight data.
- Investigating the evolutionary origin and selection history of a functional variant based on allele frequency distribution across breeds.
- Identifying candidate mutations for genomic breeding programs based on association analysis results.
- Comparing modern and ancient sheep genomes based on the absence of the mutation in historical samples.
Strengths
- Data includes analysis of 73 diverse global sheep breeds.
- Phenotypic effects were evaluated in a specific hybrid population, with statistically significant results (p < 0.05) reported.
- The mutation's absence was tested against 31 ancient European sheep genomes.
Limitations
- Row count is unknown, which may limit suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- The dataset is very small (20.3 KB), indicating limited scope.
Provenance
- Source
- figshare
- Collection Method
- Whole-genome sequencing data analysis and association analyses.
- Freshness
- Last updated 2026-04-29 05:57:40; freshness should be verified.
- Geography
- Global sheep breeds, with focus on northern Netherlands and ancient Europe.