NAD+ Metabolic Reprogramming in Colorectal Cancer Chemoresistance: Mechanistic Insights

Zhennan Ma authored a review document titled 'Table 1_The role of NAD+ metabolic reprogramming in colorectal cancer chemoresistance: mechanistic insights, clinical translation challenges and opportunities.docx'. The document discusses the core role of NAD+ metabolic reprogramming in regulating energy metabolism, DNA repair, and the immune microenvironment to drive chemoresistance. It was last updated on 2026-05-28 and is shared under a CC-BY-4.0 license.

Use Cases

• Literature review on NAD+ metabolism's role in cancer based on the described regulatory mechanisms
• Identifying translational challenges for targeted therapies based on the described barriers like tumor heterogeneity
• Exploring emerging techniques like multi-omics integration and organoid models for research based on the described future avenues

Strengths

• Document is licensed under the permissive CC-BY-4.0 license
• Last update timestamp is precisely recorded as 2026-05-28 04:49:39

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download
• Column-level documentation is absent; field semantics must be inferred after download
• The dataset is a 38.7 KB DOCX file, indicating a very limited scope likely containing a single table or review text

Provenance

Source

Zhennan Ma via figshare

Freshness

Last updated 2026-05-28 04:49:39; freshness should be verified