Table 1_Tideglusib: Novel Object Recognition Memory in DBA/2J mdx Mice

Emily N. Copeland's 2026 study reports tideglusib treatment improved recognition memory in a Duchenne muscular dystrophy mouse model. The 14.3 KB document contains results from a follow-up cognitive assessment involving novel object recognition tests and biomarker assays. Data includes measurements from male D2 wild-type and mdx mice treated with vehicle or tideglusib for four weeks.

Use Cases

• Compare recognition memory performance based on treatment group (WT, mdx-vehicle, mdx-tideglusib) mentioned in the description
• Analyze relationships between cognitive outcomes and biomarker levels (beta-catenin, Aβ, RAGE) described in the results
• Assess the effects of GSK3 inhibition on Alzheimer's-like pathology in DMD based on the study's proposed mechanism

Strengths

• Dataset is openly licensed under CC-BY-4.0, permitting reuse with attribution
• Study includes multiple biological assays (BACE1 activity, Aβ ELISA, western blotting) alongside behavioral testing

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The 14.3 KB size suggests a very limited scope, likely summary statistics rather than raw experimental data

Provenance

Source

figshare

Collection Method

Experimental data from a preclinical mouse study involving novel object recognition tests and molecular assays.

Freshness

Last updated 2026-04-22 05:48:27; freshness should be verified