Timing of Exercise Modulates Fear Memory and Neurotransmitters in Male Rats

Samuel Bennett's dataset on figshare contains results from a study on the long-term effects of chronically timed treadmill exercise on fear memory and hippocampal neurotransmitter levels in male rats. The data includes measurements from rats conditioned with a Pavlovian contextual fear approach, subjected to a 4-week exercise intervention at different circadian phases, and assessed for freezing behavior and neurotransmitter concentrations. The dataset was last updated on May 1, 2026.

Use Cases

• Analyzing the relationship between exercise timing and fear memory expression based on freezing behavior data.
• Modeling the interaction between circadian phase and neurotransmitter dynamics based on quantified hippocampal histamine, acetylcholine, and GABA levels.
• Investigating network-level reorganization of neuromodulatory tone based on weak direct neurotransmitter-freezing correlations mentioned in the description.

Strengths

• Data is associated with a detailed experimental description including a 4-week treadmill intervention and UPLC–MRM/MS quantification.
• The dataset is licensed under CC-BY-4.0, allowing for broad reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small at 16.3 KB, indicating limited scope.

Provenance

Source

Samuel Bennett via figshare.

Collection Method

Data likely gathered from a controlled laboratory experiment involving Pavlovian fear conditioning, timed treadmill exercise, and UPLC–MRM/MS analysis.

Freshness

Last updated 2026-05-01 05:27:46; freshness should be verified.