Transcriptional Profiles of Pseudomonas aeruginosa Biofilm Life Cycle Stages

Transcriptional profiling data characterizing the attachment, maturation, and dispersal stages of Pseudomonas aeruginosa PAO1 biofilms in closed cultures. The dataset, authored by Xavier Bertran Forga and last updated in April 2026, includes fold-change measurements for genes related to systems like Pil-Chp, Pel polysaccharide synthesis, and cis-2-decenoic acid sensing. It identifies fourteen genes as transcriptional biomarkers of the dispersal stage.

Use Cases

• Identify gene expression biomarkers for biofilm dispersal based on reported fold-change upregulation.
• Compare transcriptional profiles between biofilm attachment, maturation, and dispersal stages.
• Analyze the role of c-di-GMP-related enzymes and phosphodiesterases in biofilm regulation.
• Validate reporter plasmid tools for detecting the onset of biofilm dispersal.

Strengths

• Includes specific fold-change measurements for gene expression (e.g., 2.00–7.37-fold for Pil-Chp system).
• Focuses on a well-defined model organism (Pseudomonas aeruginosa PAO1) and three distinct biofilm stages.
• Licensed under CC-BY-4.0 for open reuse and redistribution.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analysis.

Provenance

Source

figshare, authored by Xavier Bertran Forga.

Collection Method

Transcriptional profiling of Pseudomonas aeruginosa PAO1 biofilm stages in closed cultures.

Time Range

The experimental time range is not specified in the provided metadata.

Freshness

Last updated 2026-04-16 05:25:28.

Geography

Spatial coverage is not specified.