Transspinal Stimulation Effects on Motor Output in Spinal Cord Injury

This dataset documents a clinical trial with 20 participants (10 with chronic spinal cord injury, 10 healthy) who received transspinal direct current stimulation (tsDCS). It evaluates changes in transspinal evoked potentials (TEPs) recruitment curves and spinal inhibitory mechanisms across multiple spinal segments before and after stimulation sessions. The study reports significant, muscle-dependent changes in motor output for specific muscles in different subject groups.

Use Cases

• Analyze TEPs recruitment input-output curves to compare spinal motor output changes between AIS A-B, AIS D, and healthy subject groups.
• Investigate TEPs homosynaptic depression and postactivation depression patterns, particularly for the right soleus and medial gastrocnemius muscles, across different subject cohorts.
• Model the muscle-dependent facilitation (distal muscles) and inhibition (proximal hip muscles) of motor output following tsDCS intervention.
• Compare the effects of an average of 15 tsDCS sessions in SCI participants versus 10 sessions in healthy participants on neurophysiological outcomes.

Strengths

• Data originates from a controlled clinical trial with a defined cohort of 20 participants.
• Includes neurophysiological measurements from 16 muscles per participant, enabling multi-muscle analysis.
• Stimulation parameters are precisely reported, with an average intensity of 2.28 ± 0.02 mA applied for one hour daily.

Limitations

• The dataset is very small (15.8 KB), likely containing summary results or a manuscript rather than raw participant-level data.
• Sample size is limited to 20 participants, which restricts statistical power and generalizability of findings.
• Specific data structure, columns, and row counts are unknown, complicating direct analysis without further clarification.

Provenance

Source

Abdullah M. Sayed Ahmad via figshare

Collection Method

Clinical trial evaluating tsDCS effects on motor neuron output and spinal inhibition in humans with and without SCI.

Time Range

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Freshness

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Geography

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