Adrenocortical Carcinoma Autophagy Protein Expression by Tumor Stage

A dataset of immunohistochemistry results for autophagy-related proteins in adrenocortical tumors. It contains expression data for ATG5, LC3B, and p62/SQSTM1 from 20 adrenocortical adenomas and 29 adrenocortical carcinomas, analyzed by tumor stage. The dataset was created by Sofia B. Oliveira and last updated on 2026-05-18.

Use Cases

• Correlating LC3B protein expression levels with tumor stage based on ENSAT classification
• Investigating the relationship between p62/SQSTM1 levels and advanced disease states
• Comparing autophagy protein expression between benign adenomas and malignant carcinomas
• Analyzing the association between LC3B expression and metastasis status

Strengths

• Includes data from 49 patient samples (20 ACA, 29 ACC), providing a basis for comparative analysis
• Reports specific, statistically significant findings, such as LC3B expression differences between tumor stages
• Links protein expression data to in vitro functional assays on cell migration and invasion

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset is small (671.0 KB), indicating limited scope

Provenance

Source

figshare

Collection Method

Immunohistochemistry on patient tissue samples and in vitro cell line experiments.

Freshness

Last updated 2026-05-18 05:41:27; freshness should be verified