Asthma Diagnosis Performance of House Dust Mite Allergen Combinations vs. Extracts

A clinical study dataset comparing the diagnostic performance of specific IgE to house dust mite extracts versus two molecular allergen combinations for asthma diagnosis. The data includes results from 201 adults with asthma and matched controls, with analysis of receiver operator characteristics and associations with type 2 inflammation biomarkers. The dataset was authored by Victoria Marrugo and last updated in April 2026.

Use Cases

• Comparing diagnostic accuracy of allergen combinations versus extracts based on receiver operator characteristics analysis.
• Modeling associations between specific IgE levels and type 2 inflammation biomarkers like fractional exhaled nitric oxide and blood eosinophils.
• Evaluating the clinical relevance of standardized, molecular-resolved diagnostic strategies for house dust mite sensitization.

Strengths

• Directly compares two diagnostic approaches (extracts vs. molecular combinations) using a defined cohort of 201 adults.
• Includes specific performance metrics like area under the curve values (e.g., 0.783, 0.808) for statistical comparison.
• Licensed under CC-BY-4.0 for open sharing and reuse.

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• The dataset is small in scale at 709.2 KB, indicating limited scope.
• Data is contained within a DOCX file, which may require extraction or conversion for analysis.

Provenance

Source

figshare

Collection Method

Clinical study comparing specific IgE measurements using receiver operator characteristics analysis.

Time Range

The study period is not specified in the provided metadata.

Freshness

Last updated 2026-04-10 05:59:05.

Geography

The geographic coverage of the patient cohort is not specified.