A case report details the branched clonal evolution of a metastatic acral melanoma under therapeutic stress. The dataset, 11.1 KB in size and last updated in May 2026, was contributed by Yuqiao Fu on figshare. It documents genetic testing results from sequential multi-site biopsies of a single patient between 2019 and 2024.
Use Cases
- Modeling clonal evolution dynamics based on sequential biopsy data mentioned in the description
- Analyzing the relationship between therapeutic pressure and mutation selection based on the case report
- Studying the co-occurrence and allele frequency changes of TERT and KIT mutations based on the reported genetic testing
- Investigating the inherent resistance of specific KIT mutations to targeted therapies like imatinib
Strengths
- Provides longitudinal genetic data from a single patient across multiple time points (2019, 2022, 2024)
- Includes results from multiple genetic testing panels (168-gene, 10-gene, single-gene) as described
- Licensed under CC-BY-4.0 for open sharing and reuse
Limitations
- Row count is unknown, which may limit suitability assessment
- Column-level documentation is absent; field semantics must be inferred after download
- The dataset's 11.1 KB size indicates it is a very small, single-case report
Provenance
- Source
- Yuqiao Fu via figshare
- Collection Method
- Case report based on clinical genetic testing of sequential tumor biopsies.
- Time Range
- Data spans from 2019 to 2024.
- Freshness
- Last updated 2026-05-20 05:45:55; freshness should be verified