Human Gut Microbiome Response to Cheddar Cheese Consumption from a 6-Week Intervention

69 participants' data from a 6-week parallel 3-armed dietary intervention study comparing unmelted cheese, melted cheese, and a deconstructed dairy control. The dataset includes demographics, anthropometry, dietary intake, and 16S rRNA gene sequencing results from fecal samples, identifying 12,098 unique bacterial taxa. The research was authored by Clíona Ní Chonnacháin and shared under a CC-BY-4.0 license on figshare.

Use Cases

• Analyze changes in bacterial alpha diversity (Shannon, Simpson) based on cheese consumption state.
• Compare differential abundance of specific taxa like Bacteroides and Dorea between intervention groups.
• Investigate the effect of food matrix alteration (melting) on overall community beta diversity.
• Model gut microbial responses using demographic and dietary intake data collected at baseline and post-intervention.

Strengths

• Data from a controlled 6-week human intervention study with 69 participants.
• Includes 16S rRNA sequencing results identifying 12,098 unique bacterial taxa.
• Statistical analysis results (e.g., FDR cutoffs, p-values) for specific microbial changes are provided.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (16.9 KB), indicating limited scope, likely containing summary results rather than raw sequence data.

Provenance

Source

figshare, author Clíona Ní Chonnacháin.

Collection Method

Secondary analysis of data from a 6-week parallel 3-armed dietary intervention study.

Time Range

Covers baseline and post-intervention timepoints from the study.

Freshness

Last updated 2026-04-10 05:29:17; freshness should be verified.

Geography

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