Vibrio cholerae N16961 Genome: Updated Functional Annotation, 2000-2026

A 2026 update provides a comparative analysis of functional annotations for the Vibrio cholerae O1 El Tor str. N16961 reference genome. The dataset tracks changes from 2000 to 2026, covering over 3500 protein-coding genes across two chromosomes. Author Ravipaul Singh presents this analysis as an easily usable resource for comparing annotation changes.

Use Cases

• Track the reduction of hypothetical protein classifications over time based on the described drop from over 40% to ~5.7%.
• Identify potential functional roles for hypothetical proteins based on the described protein-protein blast comparisons for ~38.5% of remaining entries.
• Compare historical and contemporary gene annotations for the N16961 strain based on the described 2000 vs. 2026 comparative analysis.
• Study genome structure and organization based on the described two chromosomes of ~2.96 Mbp and ~1.07 Mbp.

Strengths

• Provides a direct comparison of annotations from 2000 to a 2026 update, highlighting a quarter-century of progress.
• Focuses on a specific, well-known reference genome (V. cholerae O1 El Tor str. N16961) with over 3500 protein-coding genes.
• Includes potential functional roles for a significant portion (~38.5%) of remaining hypothetical proteins as of 2026.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale computational tasks.
• The dataset is small (170.6 KB), indicating limited scope, likely to a single genome's annotation table.

Provenance

Source

figshare, author Ravipaul Singh.

Collection Method

Comparative analysis of genomic sequencing data and protein-protein blast comparisons, as described.

Time Range

Covers annotation states from 2000 to 2026.

Freshness

Last updated 2026-05-19 05:44:47.