LILR Antibody Specificity Validation and LILRA3 ELISA Data

Hiromu Tanimoto's dataset from 2026 contains validation results for commercial antibodies targeting the Leukocyte immunoglobulin-like receptor (LILR) family. The data likely includes specificity assessments for 11 LILR members and results from a novel sandwich ELISA developed to detect the soluble LILRA3 protein. The findings highlight cross-reactivity issues and provide new monoclonal antibodies for LILRA3 detection.

Use Cases

• Validate antibody specificity for LILR family members based on flow cytometry data.
• Analyze cross-reactivity patterns among LILR receptors based on the described validation results.
• Benchmark serum concentrations of soluble LILRA3 protein using the described ELISA method.
• Identify specific antibodies for LILRA2, LILRA4, LILRA5, LILRB1, LILRB2, and LILRB4 based on the study findings.

Strengths

• Dataset is associated with a peer-reviewed study providing rigorous antibody validation.
• Includes data on novel monoclonal antibodies generated for the previously undetectable LILRA3 protein.
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• The dataset is very small (10.9 KB), indicating limited scope, likely containing summary or key results rather than raw experimental data.

Provenance

Source

figshare, author Hiromu Tanimoto

Collection Method

Data generated from flow cytometry validation of commercial antibodies on transfected K562 cells and development of a sandwich ELISA.

Freshness

Last updated 2026-04-30 04:16:49; freshness should be verified.