Table 1_Walras: LncRNA Data on Sex-Dependent ER Stress in Cardiomyopathy

Cardiovascular diseases are the leading cause of death globally, claiming an estimated 17.9 million lives annually. This document presents research data on the sex-dependent regulation of Walras and related lncRNAs in murine models of dilated and hypertrophic cardiomyopathy, authored by Francisco J. Martinez-Amaro and last updated in May 2026. The study links lncRNA activity to unfolded protein response activation, apoptosis, and mitochondrial dysfunction.

Use Cases

• Investigate sex differences in gene expression based on the described sex-dependent regulation of lncRNAs.
• Study the relationship between lncRNAs and endoplasmic reticulum stress based on the described UPR pathway activation.
• Analyze protein-protein interactions based on the described mechanism of Walras interacting with calumenin.
• Compare murine and human homologues based on the described role of APO02340.1.

Strengths

• Data is derived from multiple experimental methods including qPCR, immunochemistry, and mass spectrometry.
• Includes functional validation through assays demonstrating effects on apoptosis and mitochondrial function.
• Licensed under CC-BY-4.0 for open sharing and reuse.

Limitations

• The dataset is a 14.4 KB DOCX file, indicating a very limited scope, likely a single table or summary.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for computational analysis.

Provenance

Source

figshare

Collection Method

Generated from laboratory experiments including qPCR, immunochemistry, and mass spectrometry.

Freshness

Last updated 2026-05-11 04:28:10; freshness should be verified.