Streptococcus canis Biofilm Gene Analysis via TraDIS

A 22.6 KB dataset by Miriam Katsburg, last updated April 30, 2026. It contains results from a transposon-directed insertion site sequencing (TraDIS) study to identify genes required for biofilm formation in an infective endocarditis-causing Streptococcus canis strain. The analysis identified key genes in carbohydrate metabolism, cell wall biogenesis, and quorum sensing pathways.

Use Cases

• Identify genetic determinants of biofilm formation based on TraDIS mutant screening results.
• Analyze pathway enrichment for biofilm-associated processes like carbohydrate metabolism and quorum sensing mentioned in the description.
• Investigate host adhesion factors such as the fibronectin-binding serum opacity factor (ScSOF) in biofilm matrix composition.
• Study the inhibitory effect of carvacrol on LuxS-dependent quorum sensing in biofilm development.

Strengths

• 22.6 KB file size indicates a focused, manageable dataset for targeted analysis.
• The study provides the first genome-wide characterization of biofilm-associated gene networks in S. canis, as stated in the discussion.
• Data is licensed under CC-BY-4.0, allowing for open sharing and reuse.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (22.6 KB), indicating limited scope, likely containing summary results rather than raw sequencing data.

Provenance

Source

figshare

Collection Method

Transposon-directed insertion site sequencing (TraDIS) combined with a biofilm formation assay under flow conditions.

Freshness

Last updated 2026-04-30 05:28:58; freshness should be verified.