Feeding Intolerance and Mortality in 1,545 Critically Ill Patients

1,545 critically ill patient records from a multicenter clinical trial analyze the link between feeding intolerance and 28-day mortality. The dataset includes 856 patients who experienced feeding intolerance and 689 who did not. It was created by Youquan Wang in 2026 to identify patient subgroups more susceptible to adverse outcomes.

Use Cases

• Analyze the association between feeding intolerance status and 28-day mortality across patient subgroups like age over 65 or normal BMI.
• Investigate how primary diagnosis categories, such as respiratory disease, modify the effect of feeding intolerance on clinical outcomes.
• Examine the relationship between sequential organ failure assessment (SOFA) scores and adverse effects like ICU length of stay or ventilator-free days.

Strengths

• Contains data from 1,545 patients in a multicenter cluster-randomized controlled trial, providing a substantial clinical sample.
• Includes detailed subgroup analysis results for factors like age, BMI, primary diagnosis, and SOFA score, enabling targeted investigation.
• Derived from a secondary analysis of a published trial, ensuring a structured methodological foundation for the data.

Limitations

• The underlying data tables and specific column definitions are not provided, limiting direct analytical use.
• As a secondary analysis document, the dataset may not contain the raw patient-level data needed for novel statistical modeling.
• Subgroup findings are noted to require cautious interpretation due to multiple comparisons, indicating potential statistical limitations.

Provenance

Source

Secondary analysis of a multicenter cluster-randomized controlled trial.

Collection Method

Data extracted from patients who initiated enteral nutrition within 48 hours of ICU admission and received it for at least 3 days.

Time Range

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Freshness

Last updated in March 2026.

Geography

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