Table 10_Association of NDRG4 gene methylation in peripheral blood leukocytes with gastric

A research dataset from a two-phase case-control study of 310 gastric cancer patients and 300 controls. It analyzes the association between methylation of the NDRG4 gene in peripheral blood leukocytes and gastric cancer risk, chemotherapy efficacy, and patient prognosis. The dataset was authored by Zhan Li and last updated on 2026-04-27.

Use Cases

• Assessing gastric cancer risk based on methylation levels at specific NDRG4 CpG sites mentioned in the description
• Predicting chemotherapy efficacy for gastric cancer patients using methylation data
• Modeling progression-free survival (PFS) based on NDRG4-chr16:58497239 methylation status
• Investigating the relationship between the rs7202037 SNP genotype and NDRG4 methylation levels

Strengths

• Includes data from 610 total participants (310 patients, 300 controls) across a two-phase study design
• Reports specific statistical associations (e.g., OR=2.536 for NDRG4-chr16:58497239) with gastric cancer risk
• Links methylation data to multiple clinical endpoints: risk, chemotherapy efficacy, and progression-free survival

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The dataset is very small (15.0 KB), indicating limited scope or summary-level data

Provenance

Source

figshare

Collection Method

Data was gathered from a two-phase case-control study and bioinformatics analysis of TCGA and GEO databases.

Freshness

Last updated 2026-04-27 04:12:22; freshness should be verified