Meta-Analysis of Herbst and Twin Block Appliances for Class II Malocclusion

Franz Tito Coronel-Zubiate published a systematic review and meta-analysis comparing Herbst and Twin Block functional appliances for managing Class II malocclusion in children. The analysis includes seven randomized controlled trials with 548 participants, synthesizing evidence on skeletal, dental, and soft tissue outcomes. The review was registered with PROSPERO and the data was last updated in May 2026.

Use Cases

• Comparing treatment efficacy between Herbst and Twin Block appliances based on reported skeletal, dental, and soft tissue outcomes.
• Informing clinical decision-making for Class II malocclusion management based on meta-analysis results.
• Assessing the quality and certainty of evidence in orthodontic functional appliance research using GRADE methodology.

Strengths

• Analysis is based on seven randomized controlled trials, a standard for clinical evidence.
• The review followed a rigorous methodology including risk-of-bias assessment with Cochrane RoB 2.0 and evidence grading with GRADE.
• The dataset is openly licensed under CC-BY-4.0, permitting reuse and redistribution.

Limitations

• The dataset is a 683.4 KB DOCX file, which is a small document rather than a structured data table.
• Row and column counts are unknown, limiting suitability for direct computational analysis.
• The description provides results but not the underlying raw data from the included studies.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of published randomized controlled trials.

Time Range

Literature search up to January 30, 2025.

Freshness

Last updated 2026-05-15 07:47:31