Mouse Lung Proteome Data for Millettia Speciosa Asthma Treatment Study

Hangrui Yang published a proteomic dataset on figshare in 2026. The data includes results from a study investigating the therapeutic effects of the herb Niudali (Millettia speciosa) in an ovalbumin-induced mouse model of allergic asthma. The dataset, 366.8 KB in size, contains proteomic analysis revealing 179 differentially expressed proteins and cytokine profiling data.

Use Cases

• Identify key protein biomarkers for eosinophilic asthma based on the 179 differentially expressed proteins.
• Investigate immunometabolic pathway modulation in asthma treatment based on described changes in complement, lipid transport, and PPAR signaling.
• Validate the role of the CCL24 chemokine in allergic inflammation using the provided proteomic and cytokine data.
• Explore potential gut-lung axis mechanisms in asthma by analyzing the described molecular signature related to short-chain fatty acids.

Strengths

• Proteomic analysis identified 179 differentially expressed proteins, providing a quantitative molecular profile.
• Findings are integrated with cytokine profiling data (IgE, IL-4, IL-5, IL-6) from bronchoalveolar lavage fluid.
• Dataset is openly available under a CC-BY-4.0 license.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The study was conducted on a mouse model; direct applicability to human asthma requires further validation.

Provenance

Source

Hangrui Yang via figshare.

Collection Method

Data generated from high-resolution data-independent acquisition (DIA) lung proteomics and cytokine profiling in an ovalbumin-induced mouse model of allergic asthma.

Freshness

Last updated 2026-06-03 07:42:27; freshness should be verified.