Plasma Proteome Mendelian Randomization Data for Gastric Cancer Drug Targets

Table 11_Plasma proteome-wide Mendelian randomization reveals multi-ancestry drug targets for gastric cancer.xlsx contains results from a Mendelian randomization study identifying ancestry-specific plasma protein targets for gastric cancer. The dataset, authored by Peng Zhi and shared under a CC-BY-4.0 license, was last updated on May 1, 2026. It likely contains statistical associations for protein targets identified in European and East Asian populations.

Use Cases

• Identifying ancestry-specific causal protein targets for gastric cancer based on Mendelian randomization results
• Prioritizing drug repurposing candidates based on molecular docking results mentioned in the description
• Analyzing cellular expression patterns of protein targets in gastric tumor tissue based on single-cell RNA sequencing data
• Comparing protein target associations between European and East Asian populations based on the study's findings

Strengths

• Identifies 13 specific protein targets (4 in European, 9 in East Asian populations) associated with gastric cancer susceptibility
• Includes experimental validation results for NME4 and ICAM5 in cell lines and tissue samples
• File is shared under a permissive CC-BY-4.0 license

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The 10.4 KB file size indicates a very limited data scope, likely containing summary results only

Provenance

Source

Peng Zhi via figshare

Collection Method

Mendelian randomization and colocalization analysis of plasma proteome data

Freshness

Last updated 2026-05-01 04:19:33; freshness should be verified

Geography

European and East Asian populations