Adiponectin and Leptin Levels in IUGR and AGA Pregnancies, 200 Cases

100 IUGR and 100 AGA full-term pregnancies were analyzed for adipokine levels in maternal, umbilical cord, and neonatal blood, along with placental gene expression and DNA methylation. The dataset includes plasma concentrations of adiponectin and leptin and molecular analysis of ADIPOQ, LEP, and WFS1 genes. The data was authored by Nuzhat Parveen and last updated on 2026-05-26.

Use Cases

• Compare adipokine profiles across maternal, cord, and neonatal compartments based on the described immunoassay measurements.
• Investigate the relationship between placental gene expression and DNA methylation for adipokine-related genes like ADIPOQ and LEP.
• Model compartment-specific metabolic alterations in IUGR pregnancies based on the described differential regulation of adiponectin and leptin.

Strengths

• Case-control design with 100 IUGR and 100 AGA pregnancies provides a balanced comparison.
• Multi-compartment analysis includes maternal, umbilical cord, and neonatal blood samples.
• Combines biochemical measurements (adipokine levels) with molecular data (gene expression and DNA methylation).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small at 57.2 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Case–control study with sample collection at delivery and molecular analysis using standardized immunoassays and established techniques.

Freshness

Last updated 2026-05-26 04:37:29; freshness should be verified.