Mouse Study Data on Adipose Inflammation and Periodontitis Severity

A 2026 study by Naoaki Ryo investigates the link between obesity and periodontitis using mouse models. The dataset includes results from experiments on wild-type and CCL19-KI mice fed normal, 40%, and 60% high-fat diets, measuring alveolar bone resorption, gene expression, and serum markers. The data is stored in a 15.7 KB DOCX file.

Use Cases

• Analyze the correlation between circulating saturated fatty acids and alveolar bone resorption based on serum FFA level measurements.
• Investigate gene expression patterns in adipose tissue linked to periodontitis severity based on RNA-seq results from epididymal white adipose tissue.
• Model the combined effect of palmitic acid and osteopontin on osteoclastogenesis based on in vitro macrophage study results.

Strengths

• Data is derived from a controlled experimental study comparing three distinct diet groups and two mouse genotypes.
• Includes multiple measurement types: alveolar bone resorption, gene expression, serum FFA levels, and RNA-seq data.

Limitations

• The dataset is very small at 15.7 KB, indicating limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Experimental study using ligature-induced periodontitis in mouse models.

Freshness

Last updated 2026-05-01 05:28:40; freshness should be verified.