A genome-wide association study of 1,079 admixed Brazilian individuals identified three BMI-associated loci reaching genome-wide significance. The dataset, authored by Samantha Kuwada Teixeira and last updated in May 2026, likely contains results prioritizing a non-coding variant at chromosome 20 linked to KCNB1 and adipogenesis.
Use Cases
- Identify ancestry-informative genetic variants based on GWAS results
- Study the regulatory role of KCNB1 in adipogenesis based on functional characterization
- Analyze BMI-associated loci in admixed populations based on the Brazilian cohort
- Investigate enhancer activity and transcription factor binding based on allele-specific assays
Strengths
- Includes results from a GWAS of 1,079 individuals
- Integrates functional validation data from luciferase assays, EMSA, and animal models
- Focuses on an admixed Brazilian population, highlighting ancestry-specific mechanisms
Limitations
- Row count is unknown, which may limit suitability assessment
- Column-level documentation is absent; field semantics must be inferred after download
- The dataset is very small (14.1 KB), indicating limited scope
Provenance
- Source
- figshare
- Collection Method
- Likely contains results from a genome-wide association study and integrative analyses.
- Freshness
- Last updated 2026-05-07 04:44:58; freshness should be verified
- Geography
- Brazil