Antibiotic Resistance and Biofilm Capacity of Oral Bacteria in Caries and Healthy Patients

319 bacterial isolates from 40 participants were tested for antibiotic susceptibility and biofilm-forming capacity. The dataset, authored by David L. Auer and last updated in April 2026, shows specific taxa like Veillonella parvula exhibited distinct resistance and biofilm patterns between caries and healthy groups. Findings indicate supragingival biofilms from caries-active individuals may harbor altered antimicrobial resistance.

Use Cases

• Modeling associations between biofilm strength and antibiotic resistance based on the described findings for obligate anaerobes.
• Comparing microbial phenotypes between health and disease states using the susceptibility and biofilm data for Veillonella parvula and Lachnoanaerobaculum saburreum.
• Training classifiers to predict resistance categories from biofilm formation levels based on the optical density categorization method described.

Strengths

• Includes 319 bacterial isolates from 40 human participants, providing a clinical sample.
• Data collection used multiple standardized methods: disk diffusion, Etest, β-lactamase testing, and crystal violet staining for biofilm quantification.
• Statistical analyses accounted for clustering of isolates within individuals, suggesting careful handling of dependencies.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The dataset is very small at 29.6 KB, indicating limited scope and likely summary-level data.
• Description metadata is limited; actual data quality and granularity require manual inspection of the DOCX file.

Provenance

Source

figshare

Collection Method

Bacterial isolates were tested for antibiotic susceptibility using disk diffusion and Etest methods, with biofilm formation quantified by crystal violet staining.

Time Range

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Freshness

Last updated 2026-04-24 12:57:47; freshness should be verified.

Geography

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