Meta-Analysis of Frailty and Delirium Risk After Transcatheter Aortic Valve Replacement

Zhiheng Liu's meta-analysis document, last updated May 21, 2026, aggregates findings from 10 cohort studies involving 7,702 patients. It evaluates the association between preprocedural frailty and postoperative delirium following transcatheter aortic valve replacement, reporting pooled odds ratios and subgroup analyses. The document is a 487.9 KB DOCX file shared under a CC-BY-4.0 license on figshare.

Use Cases

• Assessing the strength of association between frailty and postoperative delirium based on the reported odds ratio of 2.17.
• Comparing effect estimates across different study characteristics, such as sample size subgroups (≥500 vs. <500).
• Evaluating the influence of different delirium diagnostic methods, like CAM-ICU vs. DSM criteria, on the reported association.
• Investigating sources of heterogeneity in meta-analyses, informed by the reported I² statistic and meta-regression results.

Strengths

• Analysis is based on a specific patient population of 7,702 individuals from 10 cohort studies.
• Provides concrete statistical results, including a pooled odds ratio of 2.17 with a 95% confidence interval of 1.60–2.95.
• Includes detailed subgroup analyses based on sample size, study design, and diagnostic methods.

Limitations

• The dataset is a single 487.9 KB document; the underlying raw data from the included studies is not provided.
• Row count and column-level documentation for any underlying tabular data are unknown.
• Freshness should be verified as the last update date is in the future (2026-05-21).

Provenance

Source

Zhiheng Liu via figshare

Collection Method

Systematic search and meta-analysis of studies from PubMed, Embase, and Web of Science.

Time Range

Studies from database inception to January 22, 2026.

Freshness

Last updated 2026-05-21 05:42:27